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  • selleck chemicals

Selleck Chemicals Medical Equipment & Supplies

725 equipment items found

Selleck Chemicals - Model A2501 - Monoclonal Antibody Targeting CD23 to Inhibit Allergen-Induced Responses

Selleck Chemicals - Model A2501 - Monoclonal Antibody Targeting CD23 to Inhibit Allergen-Induced Responses

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Lumiliximab (Anti-FceR2 / CD23) is a monoclonal antibody targeting CD23, that inhibits allergen-induced responses. MW: 145.5 ...
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Selleck Chemicals - Model A2000 - Cetuximab (anti-EGFR)

Selleck Chemicals - Model A2000 - Cetuximab (anti-EGFR)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation. MW:145.781 ...
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Selleck Chemicals - Model A2001 - Ipilimumab (anti-CTLA-4)

Selleck Chemicals - Model A2001 - Ipilimumab (anti-CTLA-4)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 ...
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Selleck Chemicals - Model A2002 - Nivolumab (anti-PD-1)

Selleck Chemicals - Model A2002 - Nivolumab (anti-PD-1)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Nivolumab (anti-PD-1) is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1,PCD-1) with immune checkpoint inhibitory and antineoplastic activities. MW : 143.597 ...
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Selleck Chemicals - Model A2003 -  Ramucirumab (anti-VEGFR2)

Selleck Chemicals - Model A2003 - Ramucirumab (anti-VEGFR2)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Ramucirumab is a monoclonal antibody of the IgG1 class that binds to VEGF-R2 and prevents its activation. The IC50 value for blocking KDR binding to VEGF is 0.8 nM for ramucirumab, MW: 143.6 ...
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Selleck Chemicals - Model A2006 - Bevacizumab (anti-VEGF)

Selleck Chemicals - Model A2006 - Bevacizumab (anti-VEGF)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Bevacizumab (anti-VEGF, Avastin) is a humanized anti-VEGF monoclonal antibody which binds to and neutralizes all human VEGF-A isoforms and bioactive proteolytic fragments, MW:149 ...
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Selleck Chemicals - Model A2007 - Trastuzumab (anti-HER2)

Selleck Chemicals - Model A2007 - Trastuzumab (anti-HER2)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Trastuzumab (anti-human HER2) is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2, MW:145.53 ...
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Selleck Chemicals - Model A2010 - Adalimumab (anti-TNF-alpha)

Selleck Chemicals - Model A2010 - Adalimumab (anti-TNF-alpha)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha, MW: 144.19 ...
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Selleck Chemicals - Model A2012 - Tocilizumab (anti-IL-6R)

Selleck Chemicals - Model A2012 - Tocilizumab (anti-IL-6R)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 ...
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Selleck Chemicals - Model A2016 - Camrelizumab (anti-PD-1)

Selleck Chemicals - Model A2016 - Camrelizumab (anti-PD-1)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Camrelizumab (anti-PD-1) is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities, MW: 146.3 ...
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Selleck Chemicals - Model A2019 - Infliximab (anti-TNF-alpha)

Selleck Chemicals - Model A2019 - Infliximab (anti-TNF-alpha)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Infliximab (anti-TNF-alpha) is a purified, recombinant DNA-derived chimeric human-mouse IgG monoclonal antibody that consists of mouse heavy and light chain variable regions combined with human heavy and light chain constant regions. Infliximab neutralizes the biological activity of TNF-α by binding with high affinity to the soluble and transmembrane forms of TNF-α, and inhibits or prevents the ...
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Selleck Chemicals - Model A2020 - Denosumab (anti-RANK ligand)

Selleck Chemicals - Model A2020 - Denosumab (anti-RANK ligand)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Denosumab (anti-RANK ligand) (AMG-162) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 ...
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Selleck Chemicals - Model A2022 - Cemiplimab (anti-PD-1)

Selleck Chemicals - Model A2022 - Cemiplimab (anti-PD-1)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Cemiplimab (anti-PD-1) is an intravenous human monoclonal antibody directed against programmed cell death-1 receptor (PD-1) and blocks its interaction with programmed death ligands 1 (PD-L1) and 2 (PD-L2). Cemiplimab blocks T-cell inactivation and enhances the immune system's anti-tumor ...
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Selleck Chemicals - Model A2024 - Ustekinumab (anti-IL-12/IL-23)

Selleck Chemicals - Model A2024 - Ustekinumab (anti-IL-12/IL-23)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Ustekinumab (CNTO 1275) is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody used to treat psoriasis. MW=145.6 ...
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Selleck Chemicals - Model A2025 - Secukinumab (anti-IL-17A)

Selleck Chemicals - Model A2025 - Secukinumab (anti-IL-17A)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Secukinumab (anti-IL-17A) (AIN457) is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is applied for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. MW=147.9 ...
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Selleck Chemicals - Model A2027 - Daratumumab (anti-CD38)

Selleck Chemicals - Model A2027 - Daratumumab (anti-CD38)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Daratumumab (anti-CD38) is a recombinant monoclonal antibody to CD38. Daratumumab is an investigational anti-cancer drug which is indicated for the treatment of adult patients with multiple myeloma. MW =145.4 ...
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Selleck Chemicals - Model A2030 - Siltuximab (anti-IL-6)

Selleck Chemicals - Model A2030 - Siltuximab (anti-IL-6)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Siltuximab (anti-IL-6) (CNTO 328) is a human-mouse chimeric monoclonal antibody that binds human interleukin-6 ...
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Selleck Chemicals - Model A2041 - Emapalumab (anti-IFNγ)

Selleck Chemicals - Model A2041 - Emapalumab (anti-IFNγ)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of pediatric and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) with ...
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Selleck Chemicals - Model A2043 - Evolocumab (anti-PCSK9)

Selleck Chemicals - Model A2043 - Evolocumab (anti-PCSK9)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Evolocumab (anti-PCSK9) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein, inhibiting it from binding to the LDLR. Evolocumab can be used for the research of hypercholesterolemia and atherosclerotic cardiovascular ...
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Selleck Chemicals - Model A2046 - Risankizumab (anti-IL-23)

Selleck Chemicals - Model A2046 - Risankizumab (anti-IL-23)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Risankizumab targets the p19 subunit of IL-23. Risankizumab is indicated for the treatment of psoriasis and is safe and effective in maintaining remission in active Crohn's ...
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